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Balance of pro-oxidant and anti-oxidants in endometriosis Epithelial cells from deep endometriotic lesions proliferate more rapidly than their normal endometrial counterparts

Trial SURMOUNT-OSA (NEJM 2024) Population 469 adults with moderate-to-severe OSA + obesity

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6) where glutathione (GSH) levels were elevated by 2-fold (47.61 6.73 mg/gprot) compared to control and superoxide dismutase (SOD) activity increased to 225.12 5.50 U/mgprot (vs 206.68 12.90), while malondialdehyde (MDA) levels were reduced to 8.88 2.19 nmol/mgprot (vs 18.21 2.10 in control), confirming the reduction of lipid peroxidation