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Sarah Woolnough, Cancer Research UK's policy director, said: "This report is further evidence that the tobacco industry should not be listened to when developing health policies aimed at reducing the devastating impact of smoking." The Tobacco Manufacturers Association claimed that more recent data showed that "the level of cigarettes consumed that are not UK tax paid has risen from 17% in 2011 to 21% in 2012" and that figures from the Office of Budget Responsibility last week showed the government expected to receive 200m less in tobacco revenue in 2012-13

The detailed calculation formulae chosen for probabilistic risk assessment are shown in Supplementary Table S2 online

The new research found that compared to smokers of other cigarette brands, the typical Natural American Spirit smoker: is younger (between 18 and 34)

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