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Tobacco use-related multimodal patterns included positive GMV in PFC, accompanied with negative GMV in insula, striatum, amygdala, parahippocampal, hippocampus and fusiform gyrus (FG)

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PAD is similar to other blood vessel diseases: Coronary artery disease affects blood flow to the heart Carotid artery disease affects blood flow to the brain Reduced blood flow to the legs can cause: Leg or hip pain when walking Feet or leg wounds that heal slowly Coolness or discoloration of the feet Numbness or weakness In severe cases, tissue damage (like gangrene) or amputation Why does diabetes increase the risk of PAD