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Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration

SAC lowered the phosphorylation levels of Smad family member 3 (Smad3) and STAT3, inhibited their binding ability to the transcription promoter, thereby restraining the transcription of fibrosis-related genes and causing the expression of antioxidant-related genes 251 (Figs

Calmangafodipir Calmangafodipir[Ca4Mn(DPDP)5, proprietary name: PledOx ], a derivative of magnetic resonance imaging contrast agent and cytoprotective agent mangafodipir, is a mitochondrial MnSOD mimetic that helps degrade tissue ROS and cells to survive oxidative stress [153]