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At US BioTek, we have not issued provocation instructions with our kits or as standard practitioner instructions because this is a clinical decision to be made with an understanding of the above factors

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PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor, PHA-665752 inhibited c-Met tyrosine phosphorylation at the activation loop (pY1230/34/35), multifunctional docking site (pY1349), and the juxtamembrane domain (pY1003) at 0.1 M [80]