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Vitamin B12 is not considered dangerous for most men, but excessive supplementation may mask underlying health issues, such as folate deficiency, if not managed with proper medical supervision

If a persons hormones are not well-controlled with medications, if they have an enlarged thyroid gland, out-of-control antibodies, Graves disease, thyroid nodules , or thyroid cancer , or are not able to have balanced thyroid hormones as they swing from hyper/hypothyroidism, some doctors may recommend surgical removal of the thyroid gland

Dehydration: May occur if you have not been drinking enough or if you have severe vomiting or have diarrhoea

This exhaustion is characterized by reduced proliferation and effector function, and is further exacerbated by the harsh conditions of the TME, including hypoxia and high levels of ROS