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Two collagen types dominate: Type I collagen (mature tendon structure) Type III collagen (early repair phase) In rodent studies, BPC-157-treated tendons showed: Increased type I collagen deposition Improved fiber parallel alignment Better biomechanical strength This suggests influence over: TGF- signalling Matrix metalloproteinases (MMPs) Extracellular matrix remodelling enzymes Balanced ECM remodelling prevents disorganized scar tissue

Front Integrative Neurosci 13:48 Li X, Zhu Q, Wang Q, Zhang Q, Zheng Y, Wang L, Jin Q (2020) Protection of sacubitril/valsartan against pathological cardiac remodeling by inhibiting the NLRP3 inflammasome after relief of pressure overload in mice

Significance of glutathione in plant adaptation to the environment