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Description

It is important to mentions that IGF-1 receptors are expressed ubiquitously [99]

pHLIP peptides target acidity in activated macrophages

Approved by the FDA in 1997 for pediatric growth hormone deficiency, it was commercially discontinued in 2008

Studies have demonstrated its ability to stimulate collagen and glycosaminoglycan synthesis, attract immune cells to sites of injury, and modulate gene expression related to tissue remodeling