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c-KIT phosphorylation directly activates p38 mitogen-activated protein kinase (MAPK), a member of the MAP kinase family, which in turn phosphorylates CREB and subsequently activates MITF to promote TYR transcription (34)

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467,468,469 Yildiz et al

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& Stucky, N

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They also showed that the addition of a P-glycoprotein inhibitor (verapamil) significantly reduced the LC 50 (the concentration that is lethal to 50% of the individuals exposed) values of ivermectin

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