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These findings were further confirmed by treatment of HDAC6 inhibitor tubacin to PC-12 cells over-expressing human mutant (A53T) -synuclein (-syn) and SH-SY5Y cells with MPP (+) that led to defects in aggresome formation accompanied by massive cell death in response to misfolded protein-induced stress (Su et al., 2011)

Fatigue : While B12 typically boosts energy, some people might initially experience fatigue as their body adjusts to the treatment

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B12 Health Benefits - Relieve the body of fatigue and weakness, potentially improving stamina - Help prevent breast cancer - Prevent anemia - Treat sickle cell anemia and Alzheimer's disease - Maintain proper heart functioning - Maintain a strong nervous system B1 Health Benefits - Contributes to energy production - Rich in anti-aging properties - Reduces Alzheimer's diseases - Maintains a healthy heart - Improves memory and appetite - Prevents cataracts - Aids in the production of red blood cells B6 Health Benefits - Aids in maintaining healthy hormone levels ~ More information, precautions and interactions can be found under the "About B Vitamins tab." Before taking any new medication, either prescription or over-the-counter, check with your doctor or pharmacist