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In addition, some scholars have investigated the high affinity of ASCT2 and ASCT1 for binding to amino acid substrates

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J Neurosci 16 : 53245333

Chronic neuroinflammation arises when persistent stimuli, including genetic mutations, pathological protein aggregates (e.g., A and -synuclein), traumatic injury, or neurotoxic exposure, convert an otherwise transient, protective inflammatory response into a sustained and maladaptive state