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Description

J Appl Toxicol 2011

The mechanistic target of rapamycin (mTOR) is the main negative regulator of autophagy

It is generally believed that vertebrate cellular GSH levels are typically in the 1-5 mM range

Rather than slowing gastric emptying or mimicking incretin hormones, tesofensine directly modulates central nervous system neurochemistry to influence appetite, satiety signaling, and energy expenditure