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[16] These mechanisms operate through different biological systems, which theoretically reduces the likelihood of direct pharmacological interaction

They have been applied in various fields, including cancer therapy, gene, protein, and enzyme delivery, solubility enhancement, transdermal and ocular delivery, drug targeting, stimuli-responsive drug delivery, diagnostic purposes, globular protein mimics, and photodynamic therapy [197]

In chronic inflammatory conditions, persistent low-grade activation or failure to transition into a reparative state drive sustained cytokine production, tissue remodeling and fibrosis, all of which predispose to disease progression (197)

They are listed here as a reference for researchers investigating BPC-157