Storage mistake If reconstituted vials sat at room temperature for an extended period, or went through repeated freeze-thaw cycles, the safer choice is to discard the vial
Protocol 1: standard longevity cycle Goal: General anti-aging and telomere maintenance Duration: 20 days active, then 4-6 months off Schedule: Days 1-20: 5 mg epitalon subcutaneously, once daily at bedtime Days 21-180: Off cycle, no epitalon Repeat cycle 1-2 times per year Reconstitution: 10 mg vial plus 2 mL bacteriostatic water equals 5 mg/mL

Poster Session I - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.03 - EPIDEMIOLOGY & RISK FACTORS P390 - ESOC25-2087 Santiago Clocchiatti-Tuozzo 1 , Cyprien Rivier 1 , Shufan Huo 1 , Ashkan Shoamanesh 2 , Hooman Kamel 3 , Santosh Murthy 3 , Adam de Havenon 1 , Lauren Sansing 1 , Thomas Gill 1 , Kevin Sheth 1 , Guido Falcone 1 1 Yale School of Medicine, New Haven, United States, 2 Faculty of Health Sciences, McMaster University, Hamilton, Canada, 3 Weill Cornell Medicine, New York, United States Background and Aims: Randomized controlled trials (RCTs) are the gold standard for evaluating treatment effects but are costly and time-consuming
In some embodiments, otic formulations described herein prolong the residence time of an active agent in the inner ear and provide a stable drug exposure profile