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SOD1 (Cytoplasmic SOD) Also known as copper-zinc SOD (Cu/Zn-SOD), SOD1 is primarily located in the cytoplasm of cells, though small amounts can also be found in the intermembrane space of mitochondria and in the nucleus

After perforin forms pores in the cell membrane, granzyme B and other proteases enter the target cell and initiate programmed cell death (115)

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