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Conclusion: PHEGAESUS presents a novel PGAS-based approach to obtain mechanistic insights and to enable personalised approaches in diagnosis and treatment of ischaemic stroke by integrating genetic and phenotypic data and circulating biomarkers

Contextual influences, such as institutional settings or competing priorities, significantly impact how stakeholders perceive and interact with these services (Findlater et al., 2021

Mechanisms affecting BBB to neurodegeneration Neurodegenerative diseases such as AD, PD, ALS, and MS, while distinct in clinical presentation, share a convergence on impaired BBB stability, CBF reduction, and vascular inflammation, reflecting parallel paths of progressive neurodegeneration distinct from acute brain injuries