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Subjects and study design Fourteen Chinese men aged 2140 years old were recruited into this duty and divided into two groups according to their BMI and insulin resistance, in detail, one group consists of seven metabolically unhealthy obese (MUO) (BMI 27.5 kg/m 2 ) that are insulin-resistant (HOMA-IR 4.34 0.41), while the other group consists of seven metabolically healthy lean (MHL) (18.5 kg/m 2 BMI 23 kg/m 2 ) who are insulin-sensitive (HOMA-IR 0.83 0.10)

Therefore, in-depth analysis of ferroptosis and its potential molecular mechanisms in human diseases may offer additional strategies for clinical prevention and treatment

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