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12 DiaoG.WangY.WangC.YangC

It is noteworthy that activating point mutations across any of the components of the pathway have been known as either trigger of cancer (mutations of RAF and RAS family genes) or as poor prognosis indicator (mutations of ERK and MEK) [114, 116]

Gynecologic Oncol (2015) 138(3):64755

found that resveratrol reduces the expression levels of ECM-related proteins such as COL1A1, FN1, -smooth muscle actin (-SMA), and -catenin in primary human leiomyoma cells, thereby inhibiting fibrotic changes in leiomyomas