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In contrast, anionic NPs, despite typically slower uptake, have been associated with Type 1 helper (Th1)-type immune responses that can support anti-inflammatory mechanisms in specific contexts [37]

Additionally, LN exhibits distinct pathological grades (IV) with varying immune infiltration and renal damage, but ferroptosis mechanisms across these grades are poorly differentiated

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As a prominent cell type in the brain, astrocytes play an important role followed brain injury ( Glycyl-l-histidyl-l-lysine (GHK) is a kind of human tripeptide consist of GHK