[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention
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Conversely, some studies show that a deficiency in vitamin B12 may cause appetite loss, potentially leading to weight loss if left untreated ( If youre low or deficient in B12, your healthcare provider will likely recommend oral vitamin B12 supplements or injections to increase your blood levels ( summary Low levels of vitamin B12 can cause megaloblastic anemia, which is characterized by shortness of breath, headaches, and fatigue
However, no significant differences were observed between ethnic groups when an interaction function was used between B 12 and ethnicity