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Our DIA-MS proteomics analysis of early ring-stage parasites demonstrated that several proteins involved in the parasite respiratory chain, a known source of reactive oxygen species (ROS) 49 , are downregulated in parasites with PfK13 mutations, and since GSH scavenges ROS 23 , less ROS could contribute to the elevated GSH levels in these resistant parasites

Patients who are following tirzepatide dosing protocols should understand that their billing pathway may affect which doses their insurance approves

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