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Signs and Symptoms Symptoms of anaphylaxis can arise swiftly and may include: Skin reactions like hives or redness Swelling in areas such as the face or mouth Breathing difficulties, including wheezing An increased or irregular heartbeat Skin that feels cold or clammy A sense of anxiety or feeling disoriented Lightheadedness or dizziness Nausea or vomiting Changes in lip color, turning blue or pale Fainting spells or lost consciousness Immediate Actions to Take Locate and Use an Epinephrine Auto-Injector : If available, administer an epinephrine injection immediately