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Goldberg MD c a Texas A&M College of Medicine, Bryan, TX b Memorial Hermann Hospital, Houston, TX c DermSurgery Associates, Houston, TX d Houston Methodist Hospital, Houston, TX Abstract BACKGROUND: Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) or drug-induced hypersensitivity (DIHS) is a rare and feared complication of frequently used medications such as anticonvulsants, sulfonamides, and allopurinol