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In lyophilized form, glutathione molecules are locked in a solid matrix with limited oxygen contact

Original Study Reference Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH

Enhancement of SAMe levels permit it to act as the cofactor of COMT, which prevents catalysis in the first step in a degradation pathway of the catecholamine neurotransmitters, and can therapeutically decrease COMT enzyme activity [183]

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