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One is multi-use safety, whereas the other is pure single-use

If redness is severe or lasts more than a few days, its a good idea to reduce how often you apply the product or switch to a lower concentration

2,3 REDEFINE 1 was a 68-week, double-blind, randomized, placebo- and active-controlled phase 3 trial that evaluated the efficacy and safety of once-weekly CagriSema versus cagrilintide 2.4 mg monotherapy, semaglutide 2.4 mg monotherapy, and placebo, all in combination with lifestyle intervention in 3,417 adults with obesity or overweight with one or more obesity-related complications and without type 2 diabetes

All in one formulation