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The strongest correlations were seen with glutathione serum transferase (GST-Pi, hour 2 concentration, immediate function group 46 25 ng/mL versus 109 40 ng/mL in the fDGF group, n = 35, p = 6.1 10 6 , Fig

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[49] synthesized new variants of HCS peptide MS1, a BIM-based peptide, which was previously engineered to have high affinity and specificity for myeloid cell leukemia-1 (Mcl-1), performing the optimization by iteration steps, and found that the conversion of staple positions is closely related to the specificity of the stapled peptide, while the unmodified template peptide (BIM SAHB A1 ) peptide possessed higher Mcl-1-specificity when the staple was located at the 2e3b position

Further, these studies have concurrently indicated that the increase of the serum selenium status leads to the corresponding increase of plasma GPx level up to a threshold and beyond that GPx activity is saturated with no further increase irrespective of the selenium status