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The lung health study: airway responsiveness to inhaled methacholine in smokers with mild to moderate airflow limitation

[39] In people requiring hospitalization, pulse oximetry, chest radiography and blood tests including a complete blood count, serum electrolytes, C-reactive protein level, and possibly liver function tests are recommended

The pretreatment times with this drug and CLP should also be presented clearly in the text

However, self-reported physician diagnosis of COPD may have high specificity and low sensitivity 41 and hence would bias the effect measure estimate towards the null but this does not explain our finding