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doi:10.1210/jc.2007-0606

Cancer 7 , 763777 (2007)

The generation of ROS by NADPH oxidase (NOX) has been linked to TNF- induced apoptosis in the rat intestinal epithelial cells-6 (IEC-6), whereas mitochondrial dysfunction along with increased mitochondrial ROS generation, has been proposed as a cause of TNF- induced apoptosis in the rat IEC (cell line RIE-1) (Babu et al