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One of the risks of this approach is that the targeted periodontal pathogens are resistant or poorly susceptible to the antibiotic drug selected, affecting the efficacy of the antimicrobial therapy, and increasing the risk of treatment failure. Although many clinical trials have shown that adjunctive systemic antibiotics combined with mechanical subgingival cleaning of the teeth offer additional clinical improvements compared to cleaning alone especially in severe disease these results are difficult to translate to everyday practice because not all patients show the same degree of long-term clinical benefit

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Aotearoa New Zealands Rapid Decline in Smoking Rates Aotearoa New Zealand has experienced a significant decline in smoking rates over the past 50 years, with a notable acceleration following the widespread adoption and legalization of nicotine vaping products in 2018