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The activation of mast cells caused the destruction of neighboring chondrocytes and the breakdown of cartilage.[ref] Related article: Osteoarthritis genes The figure below is from a study on mast cells in osteoarthritis (OA), showing both increased numbers of mast cells and an increase in tryptase

DCosta VM, King CE, Kalan L, Morar M, Sung WWL, Schwarz C, et al

All spectra were visually inspected prior to their inclusion in the analysis by a researcher blind to the group allocation

Athletes should try this approach during training to assess individual tolerance and ensure gastrointestinal comfort before applying it in competitive contexts