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In order to break this vicious cycle, insulin resistance must be taken seriously in PCOS patients

Endocrinol.2000,143, 543 43

The pentose phosphate pathway can also function as an anabolic pathway that utilizes the six carbons of glucose to generate five carbon sugars, particularly ribose-5-phosphate (R5P) that is required for purine and pyrimidine nucleotide biosynthesis