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Amy Seinfeld, D
Biochim Biophys Acta 1823:17671777
PE-22-28: TREK-1 Channel Blockade# PE-22-28 (Gly-Val-Ser-Trp-Gly-Leu-Arg) is a synthetic 7-amino acid peptide derived from spadin, itself an endogenous peptide released by proteolytic processing of sortilin (neurotensin receptor-3)
#LipidResearch #LipidAnalysis #LipidTransport #Biochemistry #LifeScienceResearch #CustomSynthesis #BOCSciences How to Analyze Lipid Transport Pathways A Practical Guide for Researchers BOC Sciences To view or add a comment, sign in Total Synthesis Meets Chemoproteomics: New Publication in Journal of Natural Products Were excited to share a new open-access publication in the Journal of Natural Products: Total Synthesis and Biological Evaluation of Leptosphaerone B and Derivatives of Microketide A. In this work, Martin Kllen, our PhD student, accomplished the total synthesis of racemic leptosphaerone B and prepared two close analogs of Microketide A, a natural product previously reported to exhibit potent activity against Gram-negative bacteria
