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NNMT inhibition increases adipose [S-adenosylmethionine (SAM)] and [Nicotinamide adenine dinucleotide (NAD+)] levels As youll discover later on in this article, theres a good reason why increased production of SAM and NAD+ within fat cells is beneficial

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This small molecule compound demonstrates exceptional ability to block nicotinamide N-methyltransferase enzyme activity, preventing NAD+ depletion while activating sirtuin pathways associated with healthy aging and metabolic optimization