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The surge in demand can be attributed to the growing awareness of the health risks associated with combustible tobacco, a shift in consumer preference towards harm-reduction products, and increasing availability of flavored, easy-to-use nicotine pouches

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Frequent Thirst: Frequent thirst is a constant urge to drink more fluids, driven by the dehydrating effects of sodas

68 More broadly, nicotine-related signaling has been linked to altered miRNA expression across multiple disease settings, supporting the idea that miRNA remodeling may represent one mechanism by which smoking leaves a persistent immunological imprint