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Warnings Smoking cigarettes is dangerous and has been linked to lung cancer and heart disease

Tobacco use is responsible for an estimated 7 million deaths each year, and this number is expected to rise to 8 million by 2030

In eight studies in which the effects of smoking cessation on endothelial function were assessed by biomarkers[19, 20, 23, 24, 30, 31, 92, 93], five studies showed that smoking cessation increased or improved biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, vvWF, ICAM-1, EPCs and EMPs and activity of eNOS [19, 23, 24, 30, 31]