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In tobacco smoke, nicotine reaches the brain within seconds and its effects last from around 30 minutes to a few hours

Whilst the overall control of TTCs in low- and middle-income countries was found to be lower and much more varied compared to high-income countries, the continuing dominance of TTCs on a global level is concerning because of their large scale and resulting level of resources that allow them to hinder tobacco control efforts

doi:10.34172/apb.2023.008 Thomas SC, Xu F, Pushalkar S, Lin Z, Thakor N, Vardhan M, Flaminio Z, Khodadadi-Jamayran A, Vasconcelos R, Akapo A, Queiroz E, Bederoff M, Janal MN, Guo Y, Aguallo D, Gordon T, Corby PM, Kamer AR, Li X, Saxena D

Where sources differed, the team investigated the gap and resolved it before accepting a figure