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Carolyn Bramante, an assistant professor of medicine at the University of Minnesota, said that while it made sense people were trying this out, she had concerns about the unknown potential effects of nicotine pouches on a person's heart and blood vessels

[35] In 1998, Brown & Williamson again found liable to pay $950,000 in damages to the relatives of a Florida resident who had died from lung cancer

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Some, like the Tobacco Control Research Branch of the National Cancer Institute, insist there is no proof that e-cigarettes help with smoking cessation