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doi: 10.1016/j.pmedr.2022.102016, 33

Metabolism of nicotine to cotinine studied by a dual stable isotope method

Why would I use a nicotine patch to quit

Professor Theresa Marteau and Ilse Lee from the University of Cambridge said: "The current study provides the first experimental evidence that people smoke more when smoking from larger pack sizes, raising the question of whether capping pack sizes might be a useful addition to existing tobacco control measures." Biochemical measures of nicotine were not taken in this study so the team couldnt assess the extent to which people may have compensated for smoking less cigarettes, perhaps by inhaling more or taking more puffs