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Oxidative stress plays a crucial role in activating and causing various cell signaling pathways that result in lesion formations of toxic substances, which foster the development of the disease

263,264 Apart from intracellular antioxidants like glutathione (GSH), heme oxygenase-1 (HO-1), superoxide dismutase-1, and nicotinamide adenine dinucleotide phosphate (NAPDH), MTs also serve as a redox buffer by interacting with and scavenging reactive species