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The reason for this is that marijuana has an inhibitory effect on the hippocampus, a region of the brain

The cardiovascular effects in adolescents are also concerning, with nicotine triggering sympathetic nervous system activation and elevation of both heart rate and blood pressure in developing cardiovascular systems [21]

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This has been caused through many people suffering from cancer and stimulation of adrenaline release that is a major cause of high blood pressure, and increased heart rates