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siRNA of NLRP3 and ASC and the negative control were synthesized by GenePharma (Shanghai, China)

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In clearing iQOS for sale in the U.S., the FDA said it delivered similar nicotine levels as conventional cigarettes, "suggesting a likelihood that IQOS users may be able to completely transition away from combustible cigarettes" and exclusively use iQOS

p=0.013) for participants who smoked more than 30 cigarettes/day compared to non-smokers