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The latter is consistent with the pseudotime analysis of our scRNA-seq data, showing that Vegfc expression is initiated in Esm1 + ECs during early steps of arterial specification and prior to Bmx expression (Supplementary Fig

Our results revealed that altered metabolomic profiles might contribute to the pathogenesis and course of MS disease by modulating immuno-inflammatory responses in the peripheral system, which is essential for eliciting autoimmune responses in the central nervous system, thus resulting in the progression of MS

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Interleukin-6 is an independent predictor of mortality in patients starting dialysis treatment