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In a review of 70 reports on social isolation, researchers found that lacking social connection was comparable to well-known risk factors for early death, including obesity, lack of exercise, and smoking 15 cigarettes a day

Clustering method Horizontal and vertical clustering: simultaneously clustering rows (such as genes, metabolites, etc.) and columns (such as samples) can help identify which features are commonly expressed in a specific set of samples

Identification of the responsible chemicals is a key avenue of further research, along with understanding the process by which they reduce the number of blood vessels

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