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found that activating transcription factor 4 (ATF4) binds to the ASNS gene promoter through Zinc Finger and BTB domain-containing protein 1 (ZBTB1) to promote ASNS transcription in drug-resistant T-cell leukemia

Although this process is not fully efficientit typically results in around 12% of consumed oxygen being converted into ROS, rather than being completely reduced to water 47,48

Treatment is GP-led by Dr Shikha Parmar and delivered under medical supervision as part of a structured six-week program tailored to the patients condition

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