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However, others have identified hemodynamic changes specifically associated with the use of ENDS containing nicotine [30], with users of ENDS presenting similar SBP and DBP to those who use combustible tobacco products [80, 81]

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Similarly, the limited number of studies conducted in long-term sole users of e-cigarettes have been completed in regional cohorts, where environmental factors, as well as the laws and restrictions on e-cigarette products, can vary

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