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In 1976 Wayne starred in his last movie, The Shootist, about an aging gunfighter who was dying of cancer

The hallmark of asthma pathophysiology is the infiltration of airway walls by inflammatory cells, such as eosinophils, T-helper 2 (Th2) lymphocytes, and mast cells (Shaik et al., 2015)

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Marano KM, Naufal ZS, Kathman SJ, Bodnar JA, Borgerding MF, Garner CD, et al