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Daily administration of two or more synaptogenic compounds simultaneously might overwhelm cellular synthetic capacity or trigger compensatory downregulation faster than either compound would alone, potentially favoring alternating administration schedules where different compounds are used on different days

Avoid repeated freeze-thaw cycles, protect from light, and use bacteriostatic water rather than sterile water for reconstitution to prevent microbial contamination during multi-dose use

Importantly, the 9-me-BC-treated rats were otherwise healthy, meaning that the results of the study can be extrapolated to potential nootropic efficacy in healthy humans, rather than, as is often the case, surmising potential effects based off of studies normally performed in either animal models of cognitive disorder, or in humans with reduced mental function

Breda PC, Wiech T, Meyer-Schwesinger C et al (2019) Renal proximal tubular epithelial cells exert immunomodulatory function by driving inflammatory CD4+ T cell responses