We can however look to side effects associated with other peptides to hypothesize what we might need to look out for.Flashes of very hot or cold temperatureChanges to appetite and/or weightDizzinessFatigueHeadaches Safety BPC-157 is generally considered safe for use
Sewastjanow-Silva, M, Xiao, L, Nogueras Gonzalez, G, Wang, X, Hofstetter, WL, Swisher, SG , Mehran, RJ, Sepesi, B, Bhutani, M, Weston, B, Coronel, E, Waters, R, Rogers, JE, Smith, J, Lyons, L, Reilly, N, Yao, JC, Ajani, JA, Blum Murphy, M
These two molecules (pBDNF and mBDNF) participate in opposing functions: pBDNF binds to p75 receptor, initiating apoptosis, or shriveling of neurons, whereas, mBDNF has primary affinity for the TrkB receptor, which mediates neuroplasticity and resilience (223, 224)
PMID: 16353210