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1 The cause of IC/BPS is unknown

The most common adverse events were gastrointestinal, and most were mild to moderate

The binding affinity of GHK for copper(II) is extremely high in the picomolar range for the apparent dissociation constant at physiological pH which means that in the presence of physiological copper, free GHK and copper-bound GHK readily interconvert with the bound form dominating

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