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Studies reporting nicotine plasma concentrations during e-cigarette use show deviating results depending on the device

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In e-liquid, freebase nicotine is usually added to a blend of VG (vegetable glycerin) and PG (propylene glycol) which act as base or 'carrier' fluids, along with flavourings

As the authors write, Some smokers live long and healthy lives while others succumb to smoking-related diseases and even death in their 40s. They also made the assumption that smokers smoked the same number of cigarettes per day across their lifetime and noted that not every cigarette smoked would affect someone in the same way each time